欢迎您注册蒲公英
您需要 登录 才可以下载或查看,没有帐号?立即注册
x
土霉素的工艺,太过粘稠了,怎么改进下。土霉素20g,氧化镁1.7g,天门冬氨酸11g,吊白块0.5g,乙醇胺6.5mL,丙二醇60mL,注射水定容至100mL。
国外工艺:
OXYTETRACYCLINE INJECTION 200 Each mL contains 200 mg oxytetracycline as base, 40.0% (w/v) 2-pyrrolidone, 5% (w/v) pvidone K17, 1.8% (w/v) magnesium oxide heavy, 0.2% (w/v) sodium formaldehyde sulphoxylate (as a preservative), monoethanolamine and/or hydrochloric acid (as required to adjust pH). 300 PRO LA (Oxytetracycline) Injection is a sterile, pre-constituted solution of the broad-spectrum antibiotic oxytetracycline dihydrate. Each mL contains 300 mg oxytetracycline as base, 40% (v/v) glycerol formal, 10% (v/v) polyethylene glycol 200, 2.7% (w/v) magnesium oxide, 0.4% (w/v) sodium formaldehyde sulphoxylate (as a preservative) and monoethanolamine (as required to adjust pH).
|