什么是placebo cleaning

beiwei5du

什么是placebo cleaning???PDA TR29中提到这个概念，仅供参考！
3.3.1.1.3 Placebo Batches as a Cleaning Method
Placebo cleaning is another type of  in-place cleaning. For certain highly viscous ointments or products,
it may be feasible to use a placebo run as a method of  cleaning equipment. This approach requires
the use of  a placebo that has no detrimental quality impact on the next product manufactured in the
equipment. The principle of  using a placebo batch for cleaning is that the action of  the placebo run-
ning through the equipment would clean the equipment of  drug residues or process residuals from
the previous batch. The advantage for this type of  cleaning is that the placebo is processed through
the equipment in the same fashion as the manufactured product. Therefore, the material would touch
the same surfaces and in the same manner as the next product batch. Disadvantages of  this method
include the cost of  cleaning and the difficulty of  demonstration of  the effectiveness of  the process.

蠡怡良

要是有中文的就好了

半世流离

一般涉及不到

beiwei5du

半世流离 发表于 2017-8-30 10:20
一般涉及不到

PAT技术支持下，并且在连续性生产概念下可能会大量涉及

半世流离

beiwei5du 发表于 2017-8-30 10:54
PAT技术支持下，并且在连续性生产概念下可能会大量涉及

恩

藏域闲居

这是一种方法，理念学习了。

beiwei5du

不知道是否有蒲友实际中有涉及到该placebo cleaning???望指教。

套路

谢谢分享，下载学习


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小金库

谢谢分享。